Technical Product Manager — Digital Health Platform

Position: Technical Product Manager — Digital Health Platform

Team: Product Management

Reports to: Head of Product

Location: Remote / Hybrid (US)

The Opportunity

Healthcare is being rebuilt by AI — not incrementally, but fundamentally. The products that will define this era are intelligent, modular platforms that learn, adapt, and act on behalf of patients and providers, with the clinical rigor to earn trust in regulated environments.

Amalgam Rx is building that platform. We sit at the intersection of clinical AI, EHR integration, pharma partnerships, and consumer-grade patient engagement — a combination that is exceptionally hard to replicate. Our modules power clinical decision support, patient companions, and health system solutions across therapeutic areas.

We’re looking for a Technical Product Manager to own the digital platform itself: the module architecture, the configurability layer, the intelligence roadmap, and the strategic conviction behind every direction it takes. You’ll be the keeper of the “why” in a fast-moving organization with no shortage of strong opinions — synthesizing market signals, reading the competitive landscape, and turning what you see into a defensible point of view that sets the platform’s course. You’ll also stand up our research preview program: releasing capabilities into the wild, instrumenting them, and turning early signal into the next round of bets.

What You’ll Do

Own the Platform

• Own the end-to-end platform strategy — module catalog, configurability, variant architecture, and roadmap.
• Define how every module evolves through three maturity stages: configurable, AI-enhanced, and agentic.
• Maintain a living platform catalog that is the first stop for every solutioning conversation, making reusability the default rather than the afterthought.
• Own the business case for platform investments — which modules to build, extend, or deprecate, and why.
• Modularize and abstract platform for maximum compatibility across diseases and care pathways and journeys.
• Define multiple user flows for same module, to adapt to different disease management programs and journeys.

Be the Keeper of Why

• Maintain a current and updated point of view on where the market, the technology, and the patient are going — and what that means for the platform six-eighteen months out.
• Track the competitive landscape with rigor: what other platforms are shipping, what pharma clients are building internally, what consumer solutions are gaining pharma attention and with patients, what hyperscalers and frontier AI labs are releasing, and which moves are signal versus noise.
• Synthesize how patient and provider expectations are shifting — what consumer AI and solutions are teaching them to expect, and what is quietly becoming table stakes.
• Defend a platform direction with evidence and conviction. Challenge consensus when the data warrants it, and surface the second-order implications before the room does.

Build, Don’t Just Specify

• Prototype platform features and module experiences using AI-assisted tools. Working demos validate ideas and earn buy-in before engineering resources are committed.
• Write developer-ready requirements: user stories, acceptance criteria, edge cases, and integration specs that engineering can pick up without translation, and be willing to defend it with engineering team.
• Continuously experiment with emerging AI and software capabilities and translate what you learn into platform bets.

Run the Product Lab

• Stand up and run Amalgam’s research preview program — a structured way to release new modules, AI capabilities, and interaction patterns to a controlled set of patients, providers, and partner pilots ahead of general availability.
• Collaborate with design team around experiments that produce real evidence: hypotheses, metrics, intervention arms, clean instrumentation, and pre-registered criteria for what would change your mind.
• Measure intervention effectiveness for both new and existing modules. Double down on what moves the outcomes that matter; retire what doesn’t.
• Close the loop from research into roadmap, platform thesis, and client conversation — partnering with clinical, regulatory, and legal so previews meet the bar for the populations we’re testing in.

Lead Discovery with Clients

• Lead the product side of early-stage client engagements: present the platform, run solution-mapping workshops, demonstrate existing modules, and scope what’s built versus configured.
• Speak the language of senior pharma stakeholders — outcomes, adherence, real-world evidence, formulary positioning — backed by a defensible view of where the market is going.
• Drive the reuse-first conversation: when a client describes a need, your instinct is to show them the module that already handles 80% of it, then negotiate the genuinely novel 20%.

Collaborate Across Functions

• Partner with engineering on architecture decisions that support modularity, configurability, and the AI-enhanced evolution of every module.
• Work with design on interaction patterns and a standard that every module feels intentional and delightful — not templated.
• Partner with data and clinical teams on the measurement infrastructure that makes the research lab credible, and with therapeutic-area product owners so their insights feed back into the roadmap.

What Success Looks Like

• The platform catalog is comprehensive, current, and instinctively used in every client conversation.
• New engagements start from existing modules. Custom builds are the exception, justified by genuine novelty.
• Modules advance through configurable → AI-enhanced → agentic on a predictable cadence.
• Leadership has a clear, current, well-defended view of where the market is heading and where the platform sits in it — because you maintain it. Strategic debates resolve faster because the framing is shared.
• The research preview program produces a steady cadence of credible findings that visibly shape the roadmap, the client narrative, and the next round of bets.
• Engineering ships faster because requirements are precise, prototypes set clear expectations, and scope debates happen before sprints, not during them.

What We’re Looking For

Experience

• 5–8 years in product management, with direct ownership of a platform, product infrastructure, or modular product system — not just individual features within someone else’s platform.
• Track record of building and scaling technology products used by large user bases — digital health, consumer health, fintech, or comparable domains where engagement, configurability, and intelligence matter.
• Demonstrated experience driving product strategy with rigor — competitive analysis, trend synthesis, thesis development — that organizations actually moved on.
• Hands-on experience with AI-powered products: personalization, recommendations, conversational AI, predictive models, or agentic workflows. You understand what AI can and cannot do, and you scope accordingly.
• Experience designing and running structured experiments in a product context — A/B tests, beta cohorts, research panels, clinical pilots — with measurable outcomes that changed the roadmap.
• Experience presenting to and negotiating with C-level or senior enterprise stakeholders in commercial settings.
• Healthcare, digital health, or life sciences experience strongly preferred. Familiarity with clinical workflows, regulatory constraints, and pharma commercial models is a significant advantage.

Demonstrated Ability

We’re looking for evidence, not just years on a résumé. The strongest candidates can:

• Walk us through a strategic call they personally defended in front of leadership — what the call was, the reasoning, what shifted along the way, and how it played out.
• Show a prototype they built themselves (not delegated) that changed a stakeholder conversation or unlocked a decision.
• Describe an experiment they designed end-to-end — hypothesis, instrumentation, what the data said, and what they did with it.
• Point to a product or capability where the fingerprints are clearly theirs.

This filters in both directions. Newer PMs without exposure to senior commercial rooms will struggle in week one. So will experienced managers who orchestrate teams but haven’t personally built, defended, or measured anything in a few years. The role lives in the middle: senior enough to hold the room, hands-on enough to ship the prototype that changes it.

Who You Are

• A builder. You prototype before you present. You’re more comfortable in a code editor or prototyping tool than in a slide deck, and you’d rather ship rough-but-real on Tuesday than polished-but-theoretical in six weeks.
• A platform thinker. You see the module, the variant model, the configurability layer, and the competitive moat at the same time. Systems excite you more than features.
• A strategist who synthesizes. You read across pharma earnings, AI research, FDA guidance, clinical literature, and competitor releases — and pull out the through-line nobody else has connected. You form sharp views, defend them with evidence, and update them when the evidence changes.
• An experimenter. Your default move when you don’t know is to design a small test, not to escalate or wait. You read results honestly, including when they tell you you were wrong.
• Entrepreneurial. You don’t wait for permission, perfect information, or a clean brief. You identify the opportunity, prototype the solution, and present the case before anyone asks. You make calls in ambiguity and course-correct quickly.
• Always learning. You have a running list of new tools, models, and capabilities you’ve explored this month — and considered opinions about each.
• A clear communicator. You explain a complex platform concept to a pharma executive in business terms and to an engineer in technical terms in the same afternoon. Your written artifacts are precise; your demos close conversations.

Why Amalgam

• You’ll own a platform, not a feature — the system everything else is built on, including the strategic thesis behind it.
• You’ll build with AI, not just manage it. Our PMs prototype with AI coding tools, use agents for catalog management and requirements generation, and push the boundary of what a product manager can articulate and build.
• You’ll run a real research lab — with clinical, regulatory, and engineering partnership to do it right.
• You’ll work on products that matter. Our platform powers clinical decisions, patient engagement, and health outcomes in regulated, real-world settings.
• You’ll move fast with a small, sharp team. No bureaucracy. Meaningful platform capabilities — and meaningful research findings — ship in days and weeks, not quarters.
• You’ll grow with the company. The platform you build, the thesis you defend, and the findings you produce will shape our programs and, if we get this right, the standard for how digital health platforms work.

Company Overview

At Amalgam Rx, our mission is to empower patients and providers to make the best decisions possible – in the provider workflow and in patients’ everyday lives. Through a suite of EHR Solutions and a modular SaMD platform, Amalgam enables the leading life sciences companies, health plans, and provider organizations to collaboratively reimagine healthcare and create lasting change across the ecosystem.

We blend art, science, and technology to create and distribute exceptional – often regulated – digital products, including digital medicine, patient identification, clinical decision support, clinical trial recruiting, and more. Our modular platform enables rapid solution creation and is directly integrated in the EHR workflow – allowing for rapid scale across health systems and around the world. Today, Amalgam’s algorithms and applications support nearly 10 million patients across 4 continents and have helped providers make over 50 million decisions.

We seek brilliant minds and passionate individuals to help us realize our vision and continue our rapid growth. We challenge each other, learn from each other, work hard, and have fun together. You’ll come to work every day with an opportunity to break new ground, and if you believe in the limitless potential of digital health, you’ll love the team.

Compensation Benefits: Amalgam offers competitive compensation, outstanding benefits, plus equity ownership for all employees.